Genetic analysis of an unequal chromosomal translocation in Aspergillus nidulans
نویسندگان
چکیده
منابع مشابه
The genetic analysis of carbohydrate utilization in Aspergillus nidulans.
SUMMARY The isolation and genetic analysis of a new class of mutants of the mould Aspergillus nidulans is described. The mutants were detected by their inability to utilize specific carbohydrates as sole carbon source for growth. All of the mutants are recessive and analysis of 27 mutants has resulted in the description of 10 new loci concerned with the utilization of carbohydrates in the organ...
متن کاملRadiation-induced chromosomal aberrations and lethals in Aspergillus nidulans.
The frequency of translocations induced in diploid conidia of Aspergillus nidulans by gamma rays was much higher than that of recessive mutants involving a single chromosome. More than half of the surviving nuclei contained viable translocations at radiation doses within the range normally employed for induction of mutants in microorganisms.
متن کاملAnalysis of mitotic nondisjunction with Aspergillus nidulans.
Two methods to detect the induction of nondisjunction with a diploid stable strain of A. nidulans are described. The first method gives only qualitative results, while the second method is quantitative and dose-effect curves can be done. Some physiological parameters affecting the induction of nondisjunction can also be studied, because either quiescent or germinating conidia can be treated wit...
متن کاملFunctional Analysis of the Aspergillus nidulans Kinome
The filamentous fungi are an ecologically important group of organisms which also have important industrial applications but devastating effects as pathogens and agents of food spoilage. Protein kinases have been implicated in the regulation of virtually all biological processes but how they regulate filamentous fungal specific processes is not understood. The filamentous fungus Aspergillus nid...
متن کاملGenetic regulation of isocitrate lyase activity in Aspergillus nidulans.
The formation of the glyoxylate cycle enzymes isocitrate lyase and malate synthase is strongly regulated in Aspergillus nidulans and the enzymes are induced at high levels in mycelium grown on acetate and found at low levels in mycelium grown on hexose. A search was made for constitutive mutants forming the enzymes when grown on hexose by the use of a pyruvate carboxylaseless (pycA) strain. Thi...
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ژورنال
عنوان ژورنال: Genetical Research
سال: 1970
ISSN: 0016-6723,1469-5073
DOI: 10.1017/s001667230000166x